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GONADOTROPIN-RELEASING HORMONE
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DeCS
Descriptor
English
:
Gonadotropin-Releasing Hormone
Descriptor
Spanish
:
Hormona Liberadora de Gonadotropina
Descriptor
Portuguese
:
Hormônio Liberador de Gonadotropina
Synonyms
English
:
FSH-Releasing Hormone
GnRH
Gonadoliberin
Gonadorelin
LH-FSH Releasing Hormone
LHRH
Luliberin
Luteinizing Hormone-Releasing Hormone
Tree Number:
D06.472.699.327.740.320
D12.644.400.400.740.320
D12.644.456.460
D12.644.548.365.740.320
D12.776.641.650.405.740.320
Definition
English
:
A decapeptide that stimulates the synthesis and secretion of both pituitary
gonadotropins
,
LUTEINIZING HORMONE
and
FOLLICLE STIMULATING HORMONE
. GnRH is produced by
neurons
in the septum
PREOPTIC AREA
of the
HYPOTHALAMUS
and released into the pituitary portal blood, leading to stimulation of
GONADOTROPHS
in the ANTERIOR
PITUITARY GLAND.
See Related
English
:
Kallmann Syndrome
Receptors, LHRH
History Note
English
:
2007 (1974)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
29311
Unique Identifier:
D007987
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS