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GROWTH HORMONE-RELEASING HORMONE
Descriptors Found:
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DeCS
Descriptor
English
:
Growth Hormone-Releasing Hormone
Descriptor
Spanish
:
Hormona Liberadora de Hormona del Crecimiento
Descriptor
Portuguese
:
Hormônio Liberador de Hormônio do Crescimento
Synonyms
English
:
Growth Hormone-Releasing Factor
Somatocrinin
Somatotropin-Releasing Factor 44
Somatotropin-Releasing Hormone
Tree Number:
D06.472.699.327.740.860
D12.644.400.400.740.860
D12.644.548.365.740.860
D12.776.641.650.405.740.860
Definition
English
:
A peptide of 44
amino acids
in most species that stimulates the release and synthesis of
GROWTH HORMONE
. GHRF (or GRF) is synthesized by
neurons
in the ARCUATE NUCLEUS of the
HYPOTHALAMUS
. After being released into the pituitary portal circulation, GHRF stimulates GH release by the
SOMATOTROPHS
in the
PITUITARY GLAND.
Indexing Annotation
English
:
DF: SRH
Pharmacological Action:
Hormones
History Note
English
:
2007 (1974)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
29298
Unique Identifier:
D013007
Occurrence in VHL
:
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DeCS
CID-10
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