Search on: NEUROSYPHILIS 
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Descriptor English:   Neurosyphilis 
Descriptor Spanish:   Neurosífilis 
Descriptor Portuguese:   Neurossífilis 
Synonyms English:   General Paresis
Paretic Neurosyphilis
Juvenile Paresis
Syphilis, Central Nervous System  
Tree Number:   C01.252.200.750
C01.252.400.840.744.456
C01.252.847.840.744.456
C10.228.228.180.600
Definition English:   Infections of the central nervous system caused by TREPONEMA PALLIDUM which present with a variety of clinical syndromes. The initial phase of infection usually causes a mild or asymptomatic meningeal reaction. The meningovascular form may present acutely as BRAIN INFARCTION. The infection may also remain subclinical for several years. Late syndromes include general paresis; TABES DORSALIS; meningeal syphilis; syphilitic OPTIC ATROPHY; and spinal syphilis. General paresis is characterized by progressive DEMENTIA; DYSARTHRIA; TREMOR; MYOCLONUS; SEIZURES; and Argyll-Robertson pupils. (Adams et al., Principles of Neurology, 6th ed, pp722-8) 
History Note English:   1963; for GENERAL PARALYSIS & PARALYSIS, GENERAL use PARESIS 1963-93 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications CN congenital
DI diagnosis DH diet therapy
DT drug therapy EC economics
EM embryology EN enzymology
EP epidemiology EH ethnology
ET etiology GE genetics
HI history IM immunology
ME metabolism MI microbiology
MO mortality NU nursing
PS parasitology PA pathology
PP physiopathology PC prevention & control
PX psychology RA radiography
RI radionuclide imaging RT radiotherapy
RH rehabilitation SU surgery
TH therapy TM transmission
US ultrasonography UR urine
VE veterinary VI virology
Record Number:   9683 
Unique Identifier:   D009494 

Occurrence in VHL:
 

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