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PROGLUCAGON
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DeCS
Descriptor
English
:
Proglucagon
Descriptor
Spanish
:
Proglucagón
Descriptor
Portuguese
:
Proglucagon
Tree Number:
D06.472.317.469
D06.472.699.587.469
D12.644.548.586.469
D12.776.811.700
Definition
English
:
The common precursor polypeptide of pancreatic
GLUCAGON
and intestinal
GLUCAGON-LIKE PEPTIDES
.
Proglucagon
is the 158-amino acid segment of preproglucagon without the N-terminal signal sequence.
Proglucagon
is expressed in the
PANCREAS
;
INTESTINES
; and the
CENTRAL NERVOUS SYSTEM
. Posttranslational processing of
proglucagon
is tissue-specific yielding numerous bioactive
peptides.
History Note
English
:
2007 (2006); for GLUCAGON PRECURSOR use GLUCAGON PRECURSOR (NM) 1977-2007
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
50566
Unique Identifier:
D052336
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS