Search on: REPLICATION PROTEIN C 
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Descriptor English:   Replication Protein C 
Descriptor Spanish:   Proteína de Replicación C 
Descriptor Portuguese:   Proteína de Replicação C 
Synonyms English:   Replication Factor C  
Tree Number:   D12.776.260.702
Definition English:   A DNA-binding protein that consists of 5 polypeptides and plays an essential role in DNA REPLICATION in eukaryotes. It binds DNA PRIMER-template junctions and recruits PROLIFERATING CELL NUCLEAR ANTIGEN and DNA POLYMERASES to the site of DNA synthesis. 
History Note English:   2006(1992) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   51055 
Unique Identifier:   D051818 

Occurrence in VHL:
 

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