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THIOINOSINE
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DeCS
Descriptor
English
:
Thioinosine
Descriptor
Spanish
:
Tioinosina
Descriptor
Portuguese
:
Tioinosina
Synonyms
English
:
6-Mercaptopurine Riboside
Tree Number:
D02.886.759.800
D03.438.759.590.616.900
D13.570.583.616.900
D13.570.800.573.900
D13.570.900.800
Definition
English
:
Sulfhydryl analog of
INOSINE
that inhibits nucleoside transport across erythrocyte
plasma
membranes
, and has immunosuppressive properties. It has been used similarly to MERCAPTOPURINE in the treatment of
leukemia
. (From Martindale, The Extra Pharmacopoeia, 30th ed, p503)
Pharmacological Action:
Antimetabolites, Antineoplastic
Immunosuppressive Agents
History Note
English
:
91(75); was see under INOSINE 1975-90
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
14250
Unique Identifier:
D013868
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
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