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ALPHA-2-ANTIPLASMIN
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DeCS
Descriptor
English
:
alpha-2-Antiplasmin
Descriptor
Spanish
:
alfa 2-Antiplasmina
Descriptor
Portuguese
:
alfa 2-Antiplasmina
Synonyms
English
:
alpha 2-Plasmin Inhibitor
Tree Number:
D12.644.861.050
D12.776.124.790.106.090
D12.776.377.715.085.090
D12.776.395.080
D12.776.872.050
Definition
English
:
A member of the
serpin superfamily
found in
plasma
that inhibits the lysis of
fibrin
clots which are induced by
plasminogen
activator. It is a glycoprotein,
molecular weight
approximately 70,000 that migrates in the alpha 2 region in
immunoelectrophoresis
. It is the principal
plasmin
inactivator in blood, rapidly forming a very stable complex with
plasmin.
Pharmacological Action:
Antifibrinolytic Agents
Serine Proteinase Inhibitors
History Note
English
:
2010(1980)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
28329
Unique Identifier:
D000979
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
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