Pesquisa sobre:
SEPARASE
Descritores Encontrados:
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DeCS
Descritor
Inglês
:
Separase
Descritor
Espanhol
:
Separasa
Descritor
Português
:
Separase
Categoria:
D08.811.277.656.262.500.792
D08.811.277.656.300.200.792
D12.776.167.552
Definição
Inglês
:
Separase
is a caspase-like
cysteine
protease, which plays a central role in triggering
ANAPHASE
by cleaving the SCC1/RAD21 subunit of the cohesin complex. Cohesin holds the sister
CHROMATIDS
together during
METAPHASE
and its cleavage results in
chromosome segregation.
Nota Histórica
Inglês
:
2014
Qualificadores Permitidos
Inglês
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número do Registro:
55268
Identificador Único:
D064247
Ocorrência na BVS
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS